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First patient treated in world-first cell therapy trial to heal the lungs of preterm babies

by xplorelab | Mar 29, 2023 | Ottawa Hospital Research Institute, Research, The Ottawa Hospital

Dr. Thébaud’s team has treated the first patient in an innovative cell therapy clinical trial – the first of its kind in the world – that aims to prevent very premature babies from developing a chronic lung disease called bronchopulmonary dysplasia (BPD)....

New publication from Xplore Lab on how a chronic lung disease in preterm babies also affects the brain

by xplorelab | Sep 22, 2022 | Ottawa Hospital Research Institute, Research, The Ottawa Hospital

A new publication uncovers clues as to why preterm babies with bronchopulmonary dysplasia (BPD) may have problems learning, thinking and remembering. A study led by former Xplore Lab team member Dr. Marissa Lithopoulos found that extra oxygen damaged the structure and...

“Cell atlas” could shine light on lung problems in premature babies and adults

by xplorelab | Apr 8, 2021 | Ottawa Hospital Research Institute, Research

Researchers have built a “cell atlas” that shows all the cellular changes that happen during the last stages of lung development. Many premature babies are born before this stage is complete and, as a result, they develop bronchopulmonary dysplasia (BPD) caused by the...

Gene therapy in development for deadly newborn lung disease

by xplorelab | Nov 4, 2020 | Funding, Ottawa Hospital Research Institute, Research, The Ottawa Hospital

A gene therapy in development by researchers at The Ottawa Hospital, CHEO and uOttawa in collaboration with the University of Guelph, is showing dramatic results in mice with this disorder, improving their life expectancy from two days to over six months, according to...

Healing damaged lungs in premature babies

by xplorelab | May 17, 2019 | Awards, Funding, Media, Ottawa Hospital Research Institute, Research

Dr. Bernard Thébaud and colleagues have been awarded $300,000 from the Ontario Institute for Regenerative Medicine (OIRM) to conduct research in preparation for a clinical trial of umbilical cord stem cell therapy for premature babies with BPD; the team hopes to...

Marissa Lithopoulos featured on The Ottawa Hospital website

by xplorelab | Jun 29, 2018 | Media, Ottawa Hospital Research Institute, Research, The Ottawa Hospital

Marissa Lithopoulos was featured on The Ottawa Hospital’s website for her work with the Let’s Talk Science outreach program, for which she has been a volunteer since 2014. This year marks the 25th anniversary of the University of Ottawa chapter of this...
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