by xplorelab | Mar 29, 2023 | Ottawa Hospital Research Institute, Research, The Ottawa Hospital
Dr. Thébaud’s team has treated the first patient in an innovative cell therapy clinical trial – the first of its kind in the world – that aims to prevent very premature babies from developing a chronic lung disease called bronchopulmonary dysplasia (BPD)....
by xplorelab | Sep 22, 2022 | Ottawa Hospital Research Institute, Research, The Ottawa Hospital
A new publication uncovers clues as to why preterm babies with bronchopulmonary dysplasia (BPD) may have problems learning, thinking and remembering. A study led by former Xplore Lab team member Dr. Marissa Lithopoulos found that extra oxygen damaged the structure and...
by xplorelab | Apr 8, 2021 | Ottawa Hospital Research Institute, Research
Researchers have built a “cell atlas” that shows all the cellular changes that happen during the last stages of lung development. Many premature babies are born before this stage is complete and, as a result, they develop bronchopulmonary dysplasia (BPD) caused by the...
by xplorelab | Nov 4, 2020 | Funding, Ottawa Hospital Research Institute, Research, The Ottawa Hospital
A gene therapy in development by researchers at The Ottawa Hospital, CHEO and uOttawa in collaboration with the University of Guelph, is showing dramatic results in mice with this disorder, improving their life expectancy from two days to over six months, according to...
by xplorelab | Jul 1, 2020 | Awards, Funding, Research
Xplore Lab and their collaborators at the University of Guelph have received a Canadian Institutes of Health Research project grant and a Collaborative Health Research Project grant to further develop an AAV vector expressing human SPB to test its potential as a...
by xplorelab | Mar 2, 2020 | Awards, Funding, Research
Dr. Bernard Thébaud and colleagues have received a $638,000 grant from the Stem Cell Network with in-kind matching funds from MDTB Cells GmbH to conduct a phase I clinical trial of umbilical cord cell therapy for premature babies. This trial aims to determine if this...
